Genius Mind · The Formula

The Science Behind
Genius Mind

Every ingredient is backed by peer-reviewed human research. This page covers what each compound does, why it is included, and the evidence behind it.

16 ingredients.
Three biological systems.

Genius Mind targets cognitive performance at three distinct levels simultaneously. Understanding the architecture helps you understand why each ingredient is there.

SYSTEM 01

Dopamine and Drive

Research suggests it may help replenish neurotransmitter precursors associated with sustained mental effort and support performance under pressure.

L-Tyrosine Panax Ginseng Guarana B-Vitamins
SYSTEM 02

Structural Repair

Some studies suggest ingredients in this group may support Nerve Growth Factor activity and neuronal membrane integrity, with effects that appear to build over time.

Lion's Mane Phosphatidylserine Zinc Citrate B-Vitamins
SYSTEM 03

Acetylcholine and Focus

Supports the availability of acetylcholine - a neurotransmitter associated with focus and memory - through both precursor supply and inhibition of its breakdown.

Choline Bitartrate Soya Lecithin Sage Leaf Bacopa Monnieri Rosemary
01

Dopamine and Drive

Research suggests these ingredients may help support neurotransmitter levels under stress and sustained effort

L-Tyrosine

3 studies

The amino acid precursor to dopamine, adrenaline, and noradrenaline. Under stress or sustained cognitive demand these are rapidly depleted. Some research suggests Tyrosine supplementation may help maintain performance under high-pressure conditions, though individual responses vary.

AcuteSteenbergen et al., 2015
Cognitive Control Under Pressure
Improved response inhibition accuracy - the ability to stop, switch, and redirect attention under high cognitive load.
AcuteDeijen & Orlebeke, 1994
Stress-Induced Memory Impairment
Prevented working memory decline caused by environmental and physiological stressors by replenishing adrenaline and noradrenaline precursors.
Systematic ReviewJongkees et al., 2016
Cognitive Flexibility
Consistent positive effect on cognitive flexibility and working memory under demanding, depleting conditions confirmed across multiple trials.

Panax Ginseng Extract

3 studies

Active ginsenosides work via two pathways: acute enhancement of working memory through neurotransmitter modulation, and longer-term reduction of mental fatigue through HPA axis adaptation. One of the few ingredients with strong evidence across both immediate and cumulative timeframes.

AcuteReay et al., 2005
Working Memory
400mg significantly improved performance on demanding "3-back" memory tasks - a gold-standard measure of working memory capacity.
8 WeeksKim et al., 2013
Mental Fatigue and Stress
Significant reduction in subjective mental fatigue during sustained cognitive activity - consistent with HPA axis and cortisol modulation.
8-9 WeeksSorensen & Sonne, 1996
Abstract Thinking and Reaction Time
Improved abstract thinking, reaction time, and concentration versus placebo across a broad cognitive test battery.

Guarana Seed Extract

2 studies

Naturally occurring caffeine bound within a seed matrix alongside theobromine and theophylline. This complex slows absorption compared to isolated caffeine, producing a more even energy curve without the sharp peak and crash.

AcuteKennedy et al., 2004
Mood and Alertness vs. Pure Caffeine
Guarana produced superior contentment and mood scores compared to equivalent caffeine alone - the natural xanthine matrix delivering a more balanced effect.
AcuteKennedy et al., 2004
Memory and Fatigue
Lower doses (75mg) outperformed higher doses on memory tasks and fatigue reduction, supporting a measured, controlled inclusion in the formula.

B-Vitamin Complex (B1, B3, B5, B6, B12)

3 studies

B-vitamins are essential co-factors in the synthesis of every major neurotransmitter including dopamine, serotonin, and noradrenaline. B5 is specifically required by the adrenal glands to produce cortisol - meaning deficiency directly impairs the stress response. This complex provides the metabolic foundation the entire formula depends on.

24 MonthsSmith et al., 2010
Brain Atrophy Prevention
B6, B9, and B12 supplementation reduced brain atrophy by up to 53% in a double-blind RCT - a landmark finding for long-term brain health.
OngoingBhatt et al., 2016
Neurotransmitter Synthesis
B-vitamins are essential co-factors in the biosynthesis of dopamine, serotonin, and norepinephrine - making deficiency a direct driver of low mood and impaired focus.
OngoingTahiliani & Beinlich, 1991
B5 and Adrenal Function
Pantothenic acid (B5) is required for coenzyme A synthesis, essential for adrenal cortisol production - linking B5 deficiency directly to impaired stress resilience.

Panax Ginseng Extract

3 studies

One of the most studied adaptogenic herbs. Research suggests Panax Ginseng may support cognitive performance under mental fatigue and help modulate the body's stress response. Effects on attention and mental clarity appear in both single-dose and multi-week trials.

8 WeeksKennedy et al., 2001
Working Memory and Calmness
Improvements in working memory quality and self-rated calmness in healthy young adults, alongside reduced reaction time on cognitive tasks.
AcuteReay et al., 2005
Mental Arithmetic and Fatigue
Significantly improved sustained mental arithmetic performance and reduced feelings of mental fatigue during a demanding cognitive task.
OngoingKim et al., 2013
Stress Response Modulation
Research suggests Panax Ginseng may help modulate the HPA axis, the system that governs the cortisol stress response, which may support performance under pressure.

Guarana Seed Extract

2 studies

Guarana contains caffeine alongside theophylline and theobromine, delivering a more sustained stimulant effect than isolated caffeine. Research suggests the combination may support alertness and cognitive performance with a smoother profile than caffeine alone.

AcuteHaskell et al., 2007
Attention and Memory
Guarana at lower doses improved secondary memory performance and increased speed of attention, outperforming isolated caffeine on several measures in a placebo-controlled trial.
AcuteKennedy et al., 2004
Cognitive Performance and Mood
Significant improvements in speed and accuracy of attention and memory tasks, alongside improved self-rated alertness and mood compared to placebo.

Zinc Citrate

2 studies

Zinc plays a structural and regulatory role in hundreds of enzymatic reactions. In the brain, it is involved in synaptic signalling and is a co-factor in the synthesis of several neurotransmitters. Research suggests zinc status is associated with attention and cognitive performance.

10 WeeksBilici et al., 2004
Attention and Impulsivity
Research found zinc supplementation was associated with meaningful improvements in attention and impulsivity measures, supporting the role of zinc status in cognitive regulation.
Systematic ReviewWarthon-Medina et al., 2015
Memory and Attention
Systematic review found consistent positive associations between zinc status and cognitive performance, particularly in domains of attention and memory.
02

Structural Repair

Some research suggests ingredients in this group may support neuronal structure and membrane integrity over time

Lion's Mane Mushroom

3 studies

Unique because of its direct effect on Nerve Growth Factor (NGF) - the protein responsible for the growth, maintenance, and repair of neurons. Some studies suggest effects may build over 8-16 weeks of consistent use.

8 WeeksKawagishi et al., 2014
Neuroprotection
Directly induced synthesis of Nerve Growth Factor in nerve cells - the protein that drives neuronal growth and repair.
16 WeeksMori et al., 2009
Cognitive Function Scale
Significant improvement in standardised cognitive scores in adults with mild cognitive impairment, reversing upon cessation - confirming the mechanism.
4 WeeksNagano et al., 2010
Anxiety and Concentration
Reduced self-reported irritation, anxiety, and concentration difficulties in healthy young adults compared to placebo.

Phosphatidylserine (from Soya Lecithin)

3 studies

A phospholipid that forms part of every neuron's outer membrane. Supplementation helps maintain membrane fluidity - critical for fast, efficient signal transmission between cells. Research also suggests it may help moderate the cortisol stress response.

AcuteMonteleone et al., 1992
Cortisol and ACTH Reduction
Significantly blunted the ACTH and cortisol response to physical stress - one of the strongest stress-hormone modulating findings in nutritional science.
2 MonthsManor et al., 2012
Attention and Short-Term Memory
Significant improvements in auditory short-term memory and inattention scores under high cognitive load conditions.
12 WeeksCrook et al., 1991
Memory and Learning
Improved learning and memory task performance in adults with memory complaints, supporting its role in neuronal membrane integrity over time.

Zinc Citrate

2 studies

An essential trace mineral involved in over 300 enzymatic processes. In the brain it acts as a neuromodulator at synapses and is essential for the zinc-finger proteins that repair neuronal DNA damage. Deficiency is common in the general population and directly impairs memory and spatial learning.

OngoingPortbury & Bhatt, 2017
Neuronal DNA Repair
Essential for zinc-finger proteins that repair neuronal DNA damage - a critical but under-discussed pathway in preserving long-term cognitive function.
OngoingWessels et al., 2017
Synaptic Signalling
Zinc's role as a synaptic neuromodulator confirmed - directly influencing neuron communication, with deficiency linked to measurable memory impairment.
03

Acetylcholine and Focus

Supports the availability of acetylcholine through precursor supply and inhibition of its breakdown enzyme

Bacopa Monnieri Extract

3 studies

One of the most rigorously studied herbal nootropics. Improves memory and reduces anxiety without causing sedation. The mechanism is dual - it inhibits acetylcholinesterase (preserving focus neurotransmitters) and promotes dendritic branching (physically building memory structures). Some studies suggest effects may peak at around 12 weeks.

12 WeeksStough et al., 2001
Information Processing Speed
Significant enhancement in the rate of visual information processing and verbal learning in healthy adults.
12 WeeksCalabrese et al., 2008
Anxiety Reduction Without Sedation
Significant anxiolytic effect while maintaining and improving attentional performance - a combination stimulants cannot achieve.
12 WeeksKongkeaw et al., 2014
Delayed Word Recall
Improved delayed recall and reduced rate of forgetting - key markers of working memory quality and long-term memory encoding.

Sage Leaf Extract

2 studies

Inhibits acetylcholinesterase - the enzyme that degrades acetylcholine in the synaptic cleft. Research suggests this mechanism may help extend the availability of acetylcholine in the brain.

1-6 HoursTildesley et al., 2005
Attention Speed and Alertness
Improved speed of attention and self-rated alertness across a 6-hour test period - among the most robust acute attention studies in the botanical literature.
AcutePerry et al., 2001
Acetylcholinesterase Inhibition
Confirmed inhibition of the enzyme that breaks down acetylcholine, effectively prolonging the brain's primary focus neurotransmitter after each dose.

Rosemary Leaf Extract

2 studies

Rosemary's active compound 1,8-cineole crosses the blood-brain barrier and inhibits acetylcholinesterase via a distinct molecular pathway from Sage - meaning the two work synergistically. Also has antioxidant properties that protect neurons from oxidative stress over time.

AcuteMoss et al., 2012
Task Accuracy Biomarker Study
Serum levels of 1,8-cineole correlated directly with higher accuracy on cognitive tasks - a rare finding linking a blood biomarker to real-world performance.
AcuteMoss & Oliver, 2012
Memory Recall Speed
Improved speed of memory recall in a randomised controlled trial versus placebo in healthy adults.

Choline Bitartrate and Soya Lecithin

2 studies

Choline is the direct dietary precursor to acetylcholine - research suggests choline availability plays an important role in acetylcholine production. Soya Lecithin provides phosphatidylcholine, the most bioavailable form, alongside phosphatidylserine. Together they are the raw material the acetylcholine system is built from.

OngoingPoly et al., 2011
Cognitive Performance and Choline Intake
Higher dietary choline intake was significantly associated with better cognitive performance across verbal and visual memory tests in a large population study.
OngoingZeisel & da Costa, 2009
Acetylcholine Synthesis
Choline availability is the rate-limiting step in acetylcholine biosynthesis - suggesting that choline intake may support the brain's capacity to produce acetylcholine.

Ginkgo Biloba Leaf Extract

2 studies

Improves cerebral blood flow, increasing delivery of oxygen and glucose to neurons. This vascular mechanism is entirely distinct from every other ingredient in the formula - with some studies showing benefits in cognitively healthy young adults, not only those with existing deficits.

6 WeeksMix & Crews, 2002
Memory and Attention in Healthy Adults
Enhanced memory recall and sustained attention in cognitively healthy young adults - evidence of benefit in the absence of any deficit.
22 WeeksAmieva et al., 2013
Cerebral Blood Flow
Enhanced cerebrovascular circulation, improving oxygen and glucose delivery to neurons - the foundational mechanism behind Ginkgo's cognitive effects.

Research on stress hormones and three formula ingredients

Chronic stress depletes dopamine and blocks memory formation. Here's how the formula addresses it.

Phosphatidylserine
Research found it significantly blunted ACTH and cortisol response to physical stress (Monteleone et al., 1992)
Monteleone et al., 1992
L-Tyrosine
Studies suggest it may help replenish catecholamine precursors depleted under stress
Deijen & Orlebeke, 1994
Panax Ginseng
Research suggests it may modulate the HPA axis - the system governing the cortisol response
Kim et al., 2013
Vitamin B5
An essential co-factor for adrenal cortisol synthesis - deficiency is associated with impaired stress response
Tahiliani & Beinlich, 1991
CONSISTENCY IS KEY . CONSISTENCY IS KEY .

Long Term Benefits

84%

saw benefits after
3 months daily use*

*Internal Survey of Genius Mind subscribers who had passed 3 months of use, April 2026 (n=56 answers).

What Happens Next

Your brain doesn't change overnight. Here's what to expect.

Genius Mind works in stages - some ingredients act within hours, others take weeks to rebuild your brain's infrastructure. We've mapped out exactly what's happening month by month.

3-month journey timeline Timeline showing Start, Month 1, Month 2, Month 3 with connecting arrows START MONTH 1 MONTH 2 MONTH 3
See Your 3-Month Journey

*These statements have not been evaluated by the Food Standards Agency or the FDA. Genius Mind is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. The studies cited are independent peer-reviewed research and do not constitute an endorsement of this product. Study references include author, publication year, and journal details for independent verification.